Severity of ischemic heart disease in relation to atherosclerotic cardiovascular risk score and individual atherosclerotic cardiovascular risk factor


Md. Rabiul Alam1 , Somaya Sidratul Montaha2


Introduction: Atherosclerotic cardiovascular disease (ASCVD) is the most common cause of ischemic heart disease that might leads to stable angina, unstable angina and myocardial infarction. The traditional risk factors for ASCVD include diabetes, hypertension, family history of premature ASCVD, Primary hypercholesterolemia, Metabolic syndrome, Chronic kidney disease, Chronic infammatory conditions, history of premature menopause and pregnancy-associated conditions, ethnicity, Lipid biomarkers abnormalities and ankle brachial index (ABI <0.9) etc. This research was intended to identify prevailing ASCVD risk factors among the study population along with their 10 years ASCVD risk scores in relation to outcome variable like different severity of coronary artery disease.

Materials and Methods: It was a cross sectional analytic study conducted from January 2020 to June 2020 in Combined Military Hospital, Dhaka. A total 100 samples were purposefully selected for this study. The individual ASCVD risk factors and 10 years ASCVD risk scores were calculated and were compared in relation to severity of ischemic heart disease. Data were analyzed by statistical package for social science version 19(SPSS-19) and p value <.05 were considered signifcant.

Results: The conventional ASCVD risk factors like smoking, DM, HTN, primary hypercholesterolemia, high LDL, low HDL, high total cholesterol, chronic infammation, metabolic syndrome and ABI were signifcantly related to the higher occurrences of severe ischemic heart disease. The others risk factors like age, stress in life, physical exercise and family H/O heart disease had no signifcant relation to the severity of ischemic heart disease. The occurrences of severe heart disease were higher in those who had intermediate or high ASCVD score than that of low ASCVD score.

Conclusion: Some traditional ASCVD risk factors and intermediate or high ASCVD score are associated with severe ischemic heart disease. However large scale study may be carried out to validate the information in Bangladesh perspective.

Keywords: ASCVD; stable angina; unstable angina; myocardial infraction

  1. ADMS

    Infantry Division, Barishal

  2. Asst. Professor, Department of Obstetrics and Gynaecology

    Z H Sikder Women’s Medical College, Dhaka

Volume 5, Number 2, July 2023
Page: 34-39